Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer

Post time 2024-4-19 10:07:28

journal：Cancer Immunology Research

Authors：Hirofumi Mikami; Shu Feng; Yutaka Matsuda; Shinya Ishii; Sotaro Naoi; Yumiko Azuma; Hiroaki Nagano; Kentaro Asanuma; Yoko Kayukawa; Toshiaki Tsunenari; Shogo Kamikawaji; Ryutaro Iwabuchi; Junko Shinozuka; Masaki Yamazaki; Haruka Kuroi; Samantha Shu Wen Ho; Siok Wan Gan; Priyanka Chichili; Chai Ling Pang; Chiew Ying Yeo; Shun Shimizu; Naoka Hironiwa; Yasuko Kinoshita; Yuichiro Shimizu; Akihisa Sakamoto; Masaru Muraoka; Noriyuki Takahashi; Tatsuya Kawa; Hirotake Shiraiwa; Futa Mimoto; Kenji Kashima; Mika Kamata-Sakurai; Shumpei Ishikawa; Hiroyuki Aburatani; Takehisa Kitazawa; Tomoyuki Igawa

Published date：--

DOI：10.1158/2326-6066.cir-23-0638

PDF link：https://aacrjournals.org/canceri ... 422/cir-23-0638.pdf

Article link：http://dx.doi.org/10.1158/2326-6066.cir-23-0638

Article Source：American Association for Cancer Research (AACR)。

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Post time 2024-4-19 10:07:29

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[AACR] Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer

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