Novel Analytical Approach to Quantify Reactive Potentially Mutagenic Sulfonate Ester Impurities in Pharmaceutical Compounds and Its Application in the Development of a Control Strategy for Nonaflate Impurities in Belzutifan Synthesis

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journal：Organic Process Research & Development

Authors：Rekha Gangam; Wenjun Liu; Michael T. Pirnot; Stephen M. Dalby; Adam J. Fine; Brittany Kassim

Published date：2022-9-16

DOI：10.1021/acs.oprd.2c00182

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00182

Article link：http://dx.doi.org/10.1021/acs.oprd.2c00182

Article Source：American Chemical Society (ACS)。


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