Abstract 3016: Tucatinib inhibits CYP3A, CYP2C8 and P-gp-mediated elimination and is impacted by CYP2C8 inhibition in healthy volunteers

Post time 2021-12-7 06:18:27

journal：Experimental and Molecular Therapeutics

Authors：Ariel R. Topletz-Erickson; Anthony Lee; Hao Sun; JoAl Mayor; Luke Walker; Christopher J. Endres

Published date：2020-8-15

DOI：10.1158/1538-7445.am2020-3016

Article link：http://dx.doi.org/10.1158/1538-7445.am2020-3016

Article Source：American Association for Cancer Research。

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Post time 2021-12-7 06:18:28

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[AACR] Abstract 3016: Tucatinib inhibits CYP3A, CYP2C8 and P-gp-mediated elimination and is impacted by CYP2C8 inhibition in healthy volunteers

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[AACR] Abstract 3016: Tucatinib inhibits CYP3A, CYP2C8 and P-gp-mediated elimination and is impacted by CYP2C8 inhibition in healthy volunteers